![]() ![]() Patients with aneurysms associated with AVM or Moyamoya disease were excluded. Aneurysms were classified as dissecting or unknown aetiology according to the classification by Isokangas et al., which defined dissecting aetiology as the lesion demonstrated a solitary or multiple irregular fusiform with or without associated narrowing of the PICA. Morphology of aneurysm was analysed carefully from angiogram. According to the classification described by Lister et al., 2 aneurysms had origin from tonsillomedullary segment, 9 from telovelotonsillar segments, and 4 from cortical segments. Four-vessel cerebral angiography performed revealed 15 distal PICA aneurysms. One patient presented with intracerebellar haemorrhage (ICH), 3 patients presented with intraventricular haemorrhage (IVH), 2 patients presented with IVH and subarachnoid haemorrhage (SAH), the other 10 patients presented with SAH. Preoperative head computed tomography (CT) and/or magnetic resonance imaging (MRI) scans were performed to confirm diagnosis. Written informed consent was obtained from all participants. This study was conducted with approval from the Ethics Committee of Jingling Hospital, School of Medicine, Nanjing University. This study was conducted in accordance with the declaration of Helsinki. There were 13 women and the mean age was 47 ± 8 years (age range, 37-59 years). This report presents the single centre experience of Onyx embolization of proximal parent artery and aneurysm in 15 patients with 15 distal PICA aneurysms.Ĭase records of 15 consecutive patients with ruptured distal PICA aneurysms treated by endovascular treatment in Jinling Hospital from October 2007 to February 2012 were retrospectively reviewed. Safety and efficacy of this treatment modality are unclear. , The existing literature concerning parent artery occlusion (PAO) with Onyx for these aneurysms is limited and is controversial. Onyx is recently used for chemoembolization for cerebral arteriovenous malformations (AVM) and aneurysms. Therapeutic options in patients with these aneurysms are unclear, endovascular treatment would be an alternative treatment option. , Clinical outcome in patients with these aneurysms after rupture is poor. Available from: ĭistal posterior inferior cerebellar artery (PICA) aneurysms arising at a peripheral segment are rare and account for 0.28-1.4% of all intracranial aneurysms. #Aica vs pica syndrome seriesParent artery occlusion with Onyx for distal aneurysms of posterior inferior cerebellar artery: A single-centre experience in a series of 15 patients. #Aica vs pica syndrome how toHow to cite this URL: Wu Q, Wang Hd, Zhang Qr, Zhang X. How to cite this article: Wu Q, Wang Hd, Zhang Qr, Zhang X. Keywords: Chemoembolization, intracranial aneurysms, Onyx, posterior inferior cerebellar artery, parent artery occlusion, therapeutic Morphology and location of aneurysm are important to decide the therapeutic strategy. Conclusions: Onyx occlusion of proximal parent artery and aneurysm in the treatment of distal PICA aneurysm is safe and effective according to this study. Aneurysmal recanalization had not been observed in any of the survived patients. None of the 14 patients had rebleeding or fresh neurologic deficits during the follow-up period. CT in 3 patients revealed cerebellar infarctions but without any neurological deficits. ![]() Head CT scan was performed in every survived patient before discharge. Fourteen patients had good recovery and the last follow-up Glasgow outcome scale was 5. One patient died because of intra-procedure haemorrhage. Results: Aneurysm was occluded completely in every patient. All patients were treated with Onyx to occlude aneurysm and proximal portion of vessel in front of aneurysm via endovascular approach. Two aneurysms had origin from tonsillomedullary segment, nine from telovelotonsillar segments, and four from cortical segments. Cerebral angiography or cerebra computed tomography-angiogram (CTA) was performed for follow-up radiological study. The follow-up ranged between 6 and 52 months. Materials and Methods: Case records of 15 consecutive patients with 15 ruptured distal PICA aneurysms treated with Onyx embolization were reviewed retrospectively. Aims: To investigate the clinical and radiologic efficacy of parent artery occlusion (PAO) with embolic agent Onyx in the treatment of distal PICA aneurysm. These aneurysms are difficult for surgical or endovascular treatment, especially for ruptured aneurysms. Background: Aneurysms located at distal posterior inferior cerebellar artery (PICA) are rare. ![]()
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